A look behind the scenes of modern Q10 formulations
Coenzyme Q10 (ubiquinone) is a vitamin-like, endogenous substance that occurs naturally in the mitochondria – the “powerhouses” of our cells. There, Q10 is involved in key steps of cellular energy production and also acts as a fat-soluble antioxidant.
What sounds simple in theory presents a major challenge in practice:
Q10 is extremely poorly soluble in water – and this significantly limits its absorption in the human intestine.
The fundamental problem with classic Q10 capsules
Conventional Q10 products usually contain crystalline coenzyme Q10, dissolved in oil or as a powder. However, the absorption of such forms is severely limited:
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Q10 is highly lipophilic (fat-loving).
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It requires bile acids and dietary fat.
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Absorption varies greatly from person to person.
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Large portions pass through the intestines unused.
The result: Two people take the same dose – but reach completely different blood levels.
🔬 The solution: What is VESIsorb® technology?
VESIsorb® technology is a patented, self-emulsifying drug delivery system (SEDDS) specifically designed for poorly soluble, fat-soluble substances such as Q10.
In short:
VESIsorb® brings Q10 into a pre-digested form that the body can absorb and utilize much more easily.
⚙️ How exactly does VESIsorb® work?
1️⃣ Self-emulsification in the digestive tract
After ingestion, the capsule comes into contact with an aqueous environment.
VESIsorb® spontaneously forms microscopically small oil-in-water droplets .
2️⃣ Massive increase in surface area
The extremely fine distribution significantly increases the contact area with the intestinal mucosa – a crucial factor for absorption.
3️⃣ Regardless of high-fat meals
Unlike classic Q10, absorption is not necessarily bound to fat or bile acids .
4️⃣ Stability until absorption
Q10 remains in a soluble, absorbable form throughout the entire passage and does not precipitate out again.
What does the research show?
A frequently cited, randomized pharmacokinetic study (Journal of Clinical Pharmacology) investigated Q10 in VESIsorb® formulation compared to conventional Q10 products.
The results (stated neutrally):
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Significantly higher plasma levels (AUC, Cmax)
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Faster inflow (Tmax)
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Up to 6 times higher bioavailability
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More even absorption between subjects
Why bioavailability is crucial
With Q10, it's not the dose on the label that matters – but what actually ends up in the blood.
A well-absorbed 100 mg dose may, under certain circumstances, produce higher blood levels than a significantly higher dose in conventional form.
This is precisely where VESIsorb® technology comes in: It does not optimize the active ingredient itself, but its physical availability to the body .
VESIsorb® in VitaRex® Q10
VitaRex® Q10 combines:
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naturally fermented coenzyme Q10
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a standardized 100 mg dose
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the patented VESIsorb® Delivery Technology
The goal is consistent, reproducible absorption , regardless of individual digestive differences.
Conclusion: Technology instead of a dosing race
The development of modern dietary supplements is currently following a clear path:
Not "more milligrams", but better absorption .
VESIsorb® technology exemplifies this approach – scientifically researched, technologically advanced and particularly suitable for lipophilic substances such as coenzyme Q10.
